Research Articles

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Browsing Research Articles by Author "Alafi, Stephen"

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    Draft genome sequence of Acinetobacter haemolyticus strain MUWRP1017 isolated from the pus of a female inpatient at Bwera General Hospital in Uganda
    (American Society for Microbiology, 2024-08-20) Wokorach, Godfrey; Erima, Bernard; Alafi, Stephen; Kabatesi, Hope O.; Muhindo, Julius T.; Najjuka, Florence; Kiyengo, James; Kibuuka, Hannah; Musinguzi, Ambrose K.; Wabwire-Mangen, Fred; Byarugaba, Denis K.
    The bacterium Acinetobacter haemolyticus, with a genome size of 3.4 Mb, was isolated from a pus swab of a wound on the left lower limb above the ankle joint of a female patient. This strain carries the antimicrobial resistance genes cephalosporinase blaADC-25, oxallinase blaOXA-264, floR, and sul2 and other resistance and virulence genes.
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    Genomic epidemiology of multidrug-resistant Escherichia coli and Klebsiella pneumoniae in Kenya, Uganda, and Jordan
    (CDC, 2024-11-11) Byarugaba, Denis K.; Osman, Tamer S.; Sayyouh, Omar M.; Wokorach, Godfrey; Kigen, Collins K.; Muturi, James W.; Onyonyi, Vanessa N.; Said, Mayar M.; Nasrat, Salwa A.; Gazo, Mahmoud; Erima, Bernard; Alafi, Stephen; Kabatesi, Hope O.; Wabwire-Mangen, Fred; Kibuuka, Hannah; Sapre, Anjali P.; Bartlett, Katelyn V.; Lebreton, Francois; Martin, Melissa J.; Mahugu, Evelyn W.; Smith, Hunter J.; Musila, Lillian A.
    Surveillance of antimicrobial resistance in Kenya, Uganda, and Jordan identified multidrug-resistant high-risk bacterial clones: Escherichia coli sequence types 131, 1193, 69, 167, 10, 648, 410, 405 and Klebsiella pneumoniae sequence types 14, 147, 307, 258. Clones emerging in those countries exhibited high resistance mechanism diversity, highlighting a serious threat for multidrug resistance.