Faculty of Health Sciences
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The Muni University’s institutional repository supports the long-term preservation of, and free access to research materials produced by members of the University.
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Research Articles [30]
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Distribution and antifungal susceptibility profile of oropharyngeal Candida species isolated from people living with HIV in the era of universal test and treat policy in Uganda
(Sage Publishing, 2024-04-30)Despite the increased frequency of oropharyngeal candidiasis among people living with human immunodeficiency virus (HIV), its management is no longer effective due to empirical treatment and emergence of antifungal resistance ... -
Sero-antigen prevalence of lymphatic filariasis and risk factors of podoconiosis in Busiriba sub-county, Kamwenge district, Southwestern Uganda, August–September 2018
(Springer Nature, 2024-05-17)Given the neglected nature of filariasis, especially in Uganda where data are scarce, this cross-sectional study aimed to determine the sero-antigen prevalence of lymphatic filariasis and risk factors associated with ... -
Plasmodium falciparum genetic diversity and multiplicity of infection based on msp-1, msp-2, glurp and microsatellite genetic markers in sub-Saharan Africa: a systematic review and meta-analysis
(Springer Nature, 2024-04-08)In sub-Saharan Africa (SSA), Plasmodium falciparum causes most of the malaria cases. Despite its crucial roles in disease severity and drug resistance, comprehensive data on Plasmodium falciparum genetic diversity and ... -
The impact of environmental and host factors on wolbachia density and efficacy as a biological tool
(Decoding Infection and Transmission, 2023-11-15)Wolbachia, a bacterium found naturally in some species of Aedes and Culex mosquitoes, has gained significant attention for it's potential in controlling mosquito-borne diseases and suppressing mosquito populations. However, ... -
A target-based discovery from a parasitic helminth as a novel therapeutic approach for autoimmune diseases.
(eBioMedicine, 2023-08-12)Background: Regulatory T cells (Tregs) can alleviate the development of autoimmune and inflammatory diseases, thereby proposing their role as a new therapeutic strategy. Parasitic helminths have co-evolved with hosts to ... -
Genomic Landscape of Epstein-Barr Virus in Endemic Burkitt Lymphoma
(Elsevier, 2023-11-29)Introduction: Endemic Burkitt lymphoma (eBL) is a fast-growing B-cell malignancy strongly linked to Epstein-Barr virus (EBV) infection, a member of the herpes virus family. The virus is widespread, infecting 95% of the ... -
Performance of a liquid biopsy diagnostic prediction model for EBV-positive Burkitt Lymphoma in Sub-Saharan Africa
(Elsevier, 2023-11-29)Burkitt Lymphoma (BL) is classified into EBV-positive BL (EBL) and EBV-negative BL (sporadic BL), the former being more prevalent in SSA (Al-Khreisat et al 2023). Conventional diagnosis of BL depends on the morphological ... -
Functioning and control of phagocytosis
(IntechOpen, 2023-04-24)Phagocytosis is a very complex and versatile process that contributes to immunity through a series of events that is it’s sometimes referred to the Come and Eat me process. Due to the recognition ingestion and digestion ... -
Investigating metabolic and molecular ecological evolution of opportunistic pulmonary fungal coinfections: protocol for a laboratory-based cross-sectional study
(JMIR Publications, 2023-04-09)Background: Fungal-bacterial cocolonization and coinfections pose an emerging challenge among patients suspected of having pulmonary tuberculosis (PTB); however, the underlying pathogenic mechanisms and microbiome ... -
“I don’t support It for my children”: perceptions of parents and guardians regarding the use of modern contraceptives by adolescents in Arua City, Uganda
(Hindawi, 2023-04-03)Despite the high rates of adolescent pregnancies, the utilization of modern contraceptives is still low among adolescents in Uganda which highlights a missed opportunity for the prevention of unwanted pregnancies among ... -
Single Nucleotide Variants (SNVs) of Angiotensin-Converting Enzymes (ACE1 and ACE2):
(Sage Publishing, 2023-04-03)Background. Although it is common knowledge that the coronavirus disease of 2019 (COVID-19) and other viral infections have an uneven impact globally, the reasons for this are still indistinct. The absence of equivalent ... -
High prevalence of malaria in pregnancy among women attending antenatal care at a large referral hospital in northwestern Uganda:
(PLOS One, 2023-04-05)Background Malaria in pregnancy contributes to substantial morbidity and mortality among women in Uganda. However, there is limited information on the prevalence and factors associated with malaria in pregnancy among women ... -
Factors associated with continuity of care in hypertension and type 2 diabetes among forcibly displaced persons in the Bidibidi refugee settlement in Uganda: Protocol for a cross-sectional, mixed-methods study
(Elsevier, 2023-03-02)Background: Non-communicable diseases in humanitarian settings are generally under-researched, particularly in Africa and have been called a neglected crisis. Little is known about factors affecting access to and (dis)continuity ... -
Persistent malnutrition among children under five in pastoral communities of Aweil centre, South Sudan
(International Journal of Scientific Research and Management (IJSRM), 2023-03)Malnutrition is one of the leading causes of morbidity and mortality among children globally, and has been linked to 60% of the 10.9M deaths annually of under-fives. High prevalence of infectious diseases contributes to ... -
Green tea silver nanoparticles improve physiological motor and cognitive function in BALB/c mice during inflammation
(Elsevier, 2023-02-21)Information on the basic changes associated with green tea small molecules in acute inflammation is deficient. The purpose of the study was to characterize and establish the effects of green tea silver nanoparticles (AgNPs) ... -
Assessment of biosafety and biorisk management practices among medical laboratory students in two institutions in Uganda
(Elsevier, 2022-09-07)Medical laboratory workers handle clinical specimens, which are a threat of exposure to infectious agents. Notably, medical laboratory science students report for internships with only theoretical knowledge of biosafety ... -
Mutactimycin AP, a new mutactimycin isolated from an actinobacteria from the Atacama Desert
(MDPI, 2022-10-24)Bacteria belonging to the phylum Actinobacteria are a very good source of antibiotics, and indeed dominate the current clinical antibiotic space. This paper reports Mutactimycin AP, a new compound belonging to an ... -
Laboratory diagnosis of candidiasis
(IntechOpen, 2022-08-04)The burden of Candidiasis continues to increase and so does the Candida species. Although Candida species are closely similar phenotypically, they differ from each other in terms of epidemiology, genetic characteristics, ... -
Ethnicity, gender, and migration status:
(Wolters Kluwer Health, 2022-07-29)Globally, 298,000 women die due to pregnancy related causes and half of this occurs in Africa. In Uganda, maternal mortality has marginally reduced from 526 to 336 per 100,000 live births between 2001 and 2016. Health ... -
In-vivo efficacy profiles of plasmodium falciparum to Artemether- Lumefantrine, the recommended first-line treatment of uncomplicated Malaria in Kisii County Kenya
(South Asian Journal of Parasitology, 2021)Place and Duration of the Study: This study was carried out in Kisii County, Kenya in 2021, during the months of February to June. Methodology: Multi-stage random sampling was used. Participants suspected to be having ...
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